Peptide • Immune, inflammation & infection

KPV

Also called Lys-Pro-Val; α-MSH fragment

What it is, the potential benefits being studied, and what the evidence supports right now.

Early laboratory researchResearch-stage compoundChecked 2026-08-21

01 • Start here

Potential benefits being studied.

Inflammation, gastrointestinal, and skin-related hypotheses.

  • Immunity & inflammation
  • Skin & hair
  • Gut & digestion

02 • Why it stands out

The simple explanation.

KPV is a tiny peptide fragment studied for calming inflammatory signaling, especially around the gut and skin.

03 • Research highlight

Why researchers are interested.

Its appeal is simple: a compact peptide with interesting anti-inflammatory biology and a growing preclinical research story.

Evidence detailsStudy limits, status, and safety context

Study summary: The evidence commonly cited for KPV is predominantly cellular and animal work in inflammation and colitis models. Meaningful controlled human therapeutic outcome evidence was not located in the current review.

What to keep in mind: Preclinical anti-inflammatory findings do not establish treatment efficacy for IBD, skin conditions, systemic inflammation, or long-term human safety.

Potential benefits describe research questions, not a promise that a product will produce the same result in a person.