Elamipretide

Also called SS-31; MTP-131

What it is, the potential benefits being studied, and what the evidence supports right now.

Well establishedUsed medically for a specific purpose

01 • Start here

Potential benefits being studied.

Barth syndrome in patients who weigh at least 30 kilograms, plus investigational research in other mitochondrial diseases.

  • Cellular energy & aging
  • Condition-specific research

02 • Why it stands out

The simple explanation.

Elamipretide is designed to work at the inner mitochondrial membrane—the energy-producing center of the cell.

03 • Research highlight

Why researchers are interested.

It is a mitochondria-focused peptide with a specific medical use and broader interest around cellular energy and muscle function.

Evidence detailsStudy limits, status, and safety context

Study summary: FDA granted accelerated approval to Forzinity in September 2025 for a narrow Barth syndrome population. Continued approval may depend on confirmatory evidence.

What to keep in mind: This approval does not establish general energy, exercise, anti-aging, or longevity benefits, or support other elamipretide products and uses.

Potential benefits describe research questions, not a promise that a product will produce the same result in a person.