Small molecule • Brain, mood & cognition
Dihexa
Also called PNB-0408; HGF/c-Met modulator
What it is, the potential benefits being studied, and what the evidence supports right now.
Early laboratory research•Research-stage compound•Checked 2026-08-21
01 • Start here
Potential benefits being studied.
Synaptogenesis, cognition, and neurodegenerative-disease hypotheses.
- Brain & cognition
02 • Why it stands out
The simple explanation.
Dihexa is getting attention for synaptogenesis, cognition, and neurodegenerative-disease hypotheses.
03 • Research highlight
Why researchers are interested.
Its biology makes synaptogenesis, cognition, and neurodegenerative-disease hypotheses an exciting early research direction.
Evidence detailsStudy limits, status, and safety context
Study summary: Published work reports HGF/c-Met signaling, hippocampal spinogenesis, and cognitive effects in animal models. Reliable human safety or efficacy trials were not identified.
What to keep in mind: Animal synaptogenesis is not human proof of memory enhancement or dementia treatment. Broad growth-signaling biology makes the absence of adequate human safety data especially important.
Potential benefits describe research questions, not a promise that a product will produce the same result in a person.